Sélection hebdomadaire des publications médicales les plus importantes.
Sources : PubMed – recommandations, revues systématiques et essais cliniques.
📋 Recommandations internationales
- From spreadsheets and scripts to controlled software lifecycles: recommendations for laboratory-developed software under ISO 15189 and IVDR
par Bas M de Haan le 02.11.2026 à 11:00Medical laboratories increasingly rely on in-house software for data processing, interpretation, and reporting of diagnostic results. Historically, such software has often taken the form of spreadsheet-based solutions or ad hoc scripts because of their accessibility and flexibility. However, evolving regulatory frameworks, most notably ISO 15189 and Regulation (EU) 2017/746 on in vitro diagnostic medical devices (IVDR), place explicit requirements on validation, traceability, risk management,...
- Correction: Prevalence of and risk factors for low anterior resection syndrome based on the international consensus definition: a multicenter cross-sectional observational studypar Yosuke Atsumi le 02.11.2026 à 11:00
No abstract
- When consensus can change hearts and minds: Sacred values and edge casespar Namrata Goyal le 02.11.2026 à 11:00
Consensus information can change people's minds, especially in ambiguous situations. But can it also change people's hearts by influencing their deeply held convictions? The literature asserts not because sacralized values are assumed to be immune to social influence. Five studies (N = 1,651) demonstrate important limits to this assumption-when facing decisions involve edge cases in which sacred boundaries are ambiguous, sacralizers are responsive to consensus information. Halal-observant...
- Consensus on Core Competencies of Undergraduate Life Sciences Students for Entry-Level Participation in Clinical Trials: RAND-Modified Delphi Studypar Ángela Cano le 02.11.2026 à 11:00
CONCLUSIONS: This consensus defines the core competencies required of undergraduate life sciences students for entry-level participation in clinical trial research. It also provides a framework for designing training strategies in both undergraduate and graduate programs of study.
- Transforming Cancer Data Ecosystems: Key Recommendations From the National Cancer Data Summitpar Anne-Marie Meyer le 02.11.2026 à 11:00
No abstract
📚 Revues systématiques et méta-analyses
- Salivary biomarkers in periodontal diseases: A systematic reviewpar Simone Sbalchiero le 02.11.2026 à 11:00
CONCLUSIONS AND PRACTICAL IMPLICATIONS: Overall, biomarker levels were associated with disease severity and generally improved after successful periodontal interventions. Matrix metalloproteinase-8 showed promising diagnostic and monitoring potential. Collectively, inflammatory, oxidative stress, and bone metabolism biomarkers may provide valuable information regarding disease activity and response to periodontal treatment. Salivary biomarkers may enable noninvasive identification of active...
- Prevalence and intensity of chronic postsurgical pain after cranial surgery: a systematic review and meta-analysis of randomized and non-randomized studiespar Ahad Daudi le 02.11.2026 à 11:00
No abstract
- Adult cancer survivors' mental health needs and experiences in primary care: a scoping reviewpar Michael Tran le 02.11.2026 à 11:00
No abstract
- Effectiveness of home-based pulmonary rehabilitation in patients with interstitial lung disease: a systematic review and meta-analysispar Chih-Chieh Huang le 02.11.2026 à 11:00
No abstract
- High-flow nasal oxygen versus non-invasive ventilation in patients with acute hypercapnic exacerbation of COPD: a systematic review and meta-analysis of randomised controlled trialspar Paraschos Archontakis Barakakis le 02.11.2026 à 11:00
No abstract
🧪 Essais cliniques majeurs
- Minimally invasive extraperitoneal reconstruction of lateral incisional hernias without posterior component separation: early multicenter outcomespar Laura Roman Garcia de Leon le 02.11.2026 à 11:00
CONCLUSION: A tailored minimally invasive preperitoneal strategy enables complete reconstruction of lateral incisional hernias without posterior component separation. These early multicenter outcomes support this strategy as an alternative for lateral abdominal wall reconstruction.
- Caring Contacts and Suicidality Among American Indian and Alaska Native Communities: A Randomized Clinical Trialpar Katherine Anne Comtois le 02.11.2026 à 11:00
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of culturally adapted Caring Contacts among American Indian or Alaska Native adults with active suicidality, Caring Contacts did not improve suicidal outcomes beyond optimal available resources alone. Similar improvements in both groups may reflect regression to the mean, the therapeutic impact of compassionate baseline engagement with supportive community staff, or the active components of optimal available resources. Further […]
- Cost-Effectiveness of Remote Symptom Monitoring During Adjuvant Endocrine Therapy in Breast Cancerpar Xin Hu le 02.11.2026 à 11:00
CONCLUSIONS AND RELEVANCE: In this economic evaluation of RPM for women receiving AET, app-only RPM showed lower costs with similar QALY compared with EUC. Its simpler design may also be more readily scalable than the app plus feedback intervention, supporting its potential as a pragmatic, value-based supportive care strategy in oncology.
- Effects of extremely low-volume high-intensity interval training combined with iron supplementation versus iron supplementation alone on postural control in young women with iron deficiency anemia: a randomized controlled trialpar Mohamed Achraf Harrabi le 02.11.2026 à 11:00
CONCLUSIONS: The study showed that women with IDA improved their postural performance regardless of the intervention used. However, an 8-week program of extremely low-volume HIIT combined with plyometric exercises and iron supplementation had a more beneficial effect compared to traditional iron therapy. These greater improvements in postural control occurred alongside greater improvements in the Hb concentration and muscle endurance in the TG compared to the NTG.
- Early patient-reported outcomes and planned persistence with lenacapavir for HIV preexposure prophylaxis in routine clinical carepar Aniruddha Hazra le 02.11.2026 à 11:00
This multicenter study evaluated early patient-reported outcomes (PROs) among individuals initiating twice-yearly lenacapavir (LEN) for HIV preexposure prophylaxis (PrEP) in routine care. Convenience, driven by reduced dosing frequency, was the primary motivation for LEN initiation, and overall satisfaction was high despite frequent but generally mild injection-site reactions. Persistent nodules and pain emerged as the leading patient-reported concerns regarding future continuation, […]